…is the remedy for deep gloom and depression that descends for no apparent reason out of a clear blue sky.
Those who are liable to times of gloom, or even despair, as though a cold dark cloud overshadowed them and hid the light and the joy of life. It may not be possible to give any reason or explanation for such attacks. Under these conditions it is almost impossible to appear happy or cheerful.
– The Twelve Healers and Other Remedies
